Texas will lift its mask requirement and allow businesses to reopen at full capacity next week, Governor Greg Abbott has announced.
Texas is the largest US state to end its mask mandate. Mr Abbott has faced criticism from his party over the measure, which was imposed last July.
But the administration of US President Joe Biden has made it clear coronavirus restrictions are still necessary.
The announcement in Texas came as similar rules were lifted in other states, including Michigan, Louisiana, and Mississippi, which also ended its mask mandate.
The roll-out of vaccinations against Covid-19 has boosted confidence in a return to pre-pandemic life in the US.
On Monday the director of the US Centers for Disease Control and Prevention (CDC) warned of a “potential fourth surge of cases” if the country lapsed into complacency.
According to data collated by Johns Hopkins University, in total, the US has recorded more than 28 million infections and 516,000 deaths related to Covid-19.